Identification of potential apicoplast associated therapeutic targets in human and animal pathogen Toxoplasma gondii ME49
نویسندگان
چکیده
منابع مشابه
Identification of potential apicoplast associated therapeutic targets in human and animal pathogen Toxoplasma gondii ME49
UNLABELLED Toxoplasma gondii ME49 is an obligatory intracellular apicomplexa parasite that causes toxoplasmosis in humans, domesticated and wild animals. Waterborne outbreaks of acute toxoplasmosis worldwide reinforce the transmission of Toxoplasma gondii ME49 to humans through contaminated water and may have a greater epidemiological impact than previously believed. In the quest for drug and v...
متن کاملToxoplasma gondii Tic20 is essential for apicoplast protein import.
Apicomplexan parasites harbor a secondary plastid that has lost the ability to photosynthesize yet is essential for the parasite to multiply and cause disease. Bioinformatic analyses predict that 5-10% of all proteins encoded in the parasite genome function within this organelle. However, the mechanisms and molecules that mediate import of such large numbers of cargo proteins across the four me...
متن کاملMolecular identification of Brucella species and biovars associated with animal and human infection in Iran
Brucellosis is a costly contagious disease of human, domestic and wild animals. It is a serious health problem in Iran causing significant economic losses therefore, control approaches to prevent its spread are of great importance. In Iran, the species and biovars of virulent Brucella species are still under-reported due to the inadequate diagnostic protocols and insufficient laborator...
متن کاملPlatelet proteomics: identification of potential therapeutic targets.
The integration of proteomics into biochemical and biological investigation has proved a powerful tool in understanding the anucleate platelet. Over the past few years, various approaches have been used to document platelet proteins and here, we describe our efforts to analyse specific platelet subproteomes so as to capture biologically relevant proteins of low abundance. These include characte...
متن کاملSeroprevalence and risk factors associated with Toxoplasma gondii infection in sheep of Veracruz State, southeast Mexico
Toxoplasma gondii is widely prevalent in sheep and their products pose a risk to public health. The aim of this study was to identify the seroprevalence and risk factors associated with T. gondii infection in sheep in Veracruz State, Mexico. The study was cross-sectional and it was carried out in thirteen municipalities distributed in three regions of Veracruz State. A total o...
متن کاملذخیره در منابع من
با ذخیره ی این منبع در منابع من، دسترسی به آن را برای استفاده های بعدی آسان تر کنید
ژورنال
عنوان ژورنال: Bioinformation
سال: 2011
ISSN: 0973-8894,0973-2063
DOI: 10.6026/97320630007379